As many of us with Lyme Disease already know, we are usually infected with more than one kind of bug. Today, I want to talk about what I’ve learned about Candida and my efforts to overcome it.
I believe that Candida is one of my worst problems, leading to gut permeability, food “allergies”, inflammation, and chronic headaches. I first figured out that I had a Candida problem in 2008 when my research on headaches and food allergies led me to this as a probable cause. After trying a few natural supplements and probiotics to no avail, I started taking oral Nystatin powder. Bingo! I had my first remission of headaches and misery in years. I was able to eat a wider variety of foods. But the effects were short lived. It seems the effectiveness of Nystatin wore off within months.
After trying numerous other natural and pharmaceutical antifungals and clays for gut detox, I had only slight and short-lived relief. Then my doctor put me on Butyrate in 2012. I didn’t realize it at the time, but that was probably a major contributor to my improved health last year. That, along with NAET/BioSET treatments, toxin binders, and high doses of methylfolate to improve my detox system.
I discussed Butyrate in a previous post. Not only does it mop up excess ammonia, quell food allergies, and soothe the gut, but it actually disables the more virulent hyphal form of Candida. Following is some research I came across discussing the role of short-chain fatty acids (SCFA’s) on gut health and Candida.
The American Society for Microbiology provides free access to full text articles on Candida and other fungal infections. Here is a link to an article in the Journal of Infectious Immunology from 2004 titled Regulation of Candida albicans Morphogenesis by Fatty Acid Metabolites: http://iai.asm.org/content/72/11/6206.full.pdf+html. Briefly, this article talks about how fatty acids disable the conversion of Candida albicans into their more virulent hyphal form that burrows into tissues.
And here is link to another article in the journal Eukaryotic Cell titled Conjugated Linoleic Acid Inhibits Hyphal Growth in Candida albicans by Modulating Ras1p Cellular Levels and Downregulating TEC1 Expression: http://ec.asm.org/content/10/4/565.full.pdf+html. The gist of this article is that CLA stops the virulent hyphal form of Candida.
In my ignorance and efforts to save money, I gradually stopped taking Butyrate, or only took it sporadically. I started it again at a high dose of 600mg, 8 caps per day, and have noticed a reduction in food-related headaches. So in order for me to eat enough to survive, I take 2 capsules of activated charcoal or clay 30 min before a meal, and 4 caps of butyrate at the end of a meal. Hopefully, this is a short term fix until I can actually kill off my gut infections for good.
My doctor also has me on Pau d’arco, a South American herb known for its antimicrobial properties. I make it into a tea and drink it twice per day. It tastes nice, like root beer. So far it has no side effects for me at this dose. Lapachol is a compound in Pau d’arco that is known to kill Candida. You can look this up in PubMed.gov and come up with journals discussing the research. Here is one source: http://www.ncbi.nlm.nih.gov/pubmed/7938274.
My next step with Candida is to try oxygen therapies, like ozone or oral liquid oxygen products to see if I can really kill it off instead of just keeping it at bay with fungistatic compounds and diet.